diff --git a/apm-sniffer/apm-agent-core/src/main/java/org/skywalking/apm/agent/core/plugin/AbstractClassEnhancePluginDefine.java b/apm-sniffer/apm-agent-core/src/main/java/org/skywalking/apm/agent/core/plugin/AbstractClassEnhancePluginDefine.java
index 2c16b2866..f4cda7556 100644
--- a/apm-sniffer/apm-agent-core/src/main/java/org/skywalking/apm/agent/core/plugin/AbstractClassEnhancePluginDefine.java
+++ b/apm-sniffer/apm-agent-core/src/main/java/org/skywalking/apm/agent/core/plugin/AbstractClassEnhancePluginDefine.java
@@ -24,7 +24,7 @@ public abstract class AbstractClassEnhancePluginDefine {
      *
      * @param transformClassName target class.
      * @param builder            byte-buddy's builder to manipulate target class's bytecode.
-     * @return be defined builder.
+     * @return the new builder, or <code>null</code> if not be enhanced.
      * @throws PluginException, when set builder failure.
      */
     public DynamicType.Builder<?> define(String transformClassName,
@@ -33,7 +33,7 @@ public abstract class AbstractClassEnhancePluginDefine {
 
         if (StringUtil.isEmpty(transformClassName)) {
             logger.warn("classname of being intercepted is not defined by {}.", interceptorDefineClassName);
-            return builder;
+            return null;
         }
 
         logger.debug("prepare to enhance class {} by {}.", transformClassName, interceptorDefineClassName);
@@ -48,7 +48,7 @@ public abstract class AbstractClassEnhancePluginDefine {
                 if (!witnessClassResolution.isResolved()) {
                     logger.warn("enhance class {} by plugin {} is not working. Because witness class {} is not existed.", transformClassName, interceptorDefineClassName,
                         witnessClass);
-                    return builder;
+                    return null;
                 }
             }
         }
diff --git a/apm-sniffer/apm-agent-core/src/main/java/org/skywalking/apm/agent/core/plugin/PluginFinder.java b/apm-sniffer/apm-agent-core/src/main/java/org/skywalking/apm/agent/core/plugin/PluginFinder.java
index 2caa7214b..45ce1d5b5 100644
--- a/apm-sniffer/apm-agent-core/src/main/java/org/skywalking/apm/agent/core/plugin/PluginFinder.java
+++ b/apm-sniffer/apm-agent-core/src/main/java/org/skywalking/apm/agent/core/plugin/PluginFinder.java
@@ -1,6 +1,7 @@
 package org.skywalking.apm.agent.core.plugin;
 
 import java.util.HashMap;
+import java.util.LinkedList;
 import java.util.List;
 import java.util.Map;
 
@@ -11,7 +12,7 @@ import java.util.Map;
  * @author wusheng
  */
 public class PluginFinder {
-    private final Map<String, AbstractClassEnhancePluginDefine> pluginDefineMap = new HashMap<String, AbstractClassEnhancePluginDefine>();
+    private final Map<String, LinkedList<AbstractClassEnhancePluginDefine>> pluginDefineMap = new HashMap<String, LinkedList<AbstractClassEnhancePluginDefine>>();
 
     public PluginFinder(List<AbstractClassEnhancePluginDefine> plugins) {
         for (AbstractClassEnhancePluginDefine plugin : plugins) {
@@ -21,11 +22,17 @@ public class PluginFinder {
                 continue;
             }
 
-            pluginDefineMap.put(enhanceClassName, plugin);
+            LinkedList<AbstractClassEnhancePluginDefine> pluginDefinesWithSameTarget = pluginDefineMap.get(enhanceClassName);
+            if (pluginDefinesWithSameTarget == null) {
+                pluginDefinesWithSameTarget = new LinkedList<AbstractClassEnhancePluginDefine>();
+                pluginDefineMap.put(enhanceClassName, pluginDefinesWithSameTarget);
+            }
+
+            pluginDefinesWithSameTarget.add(plugin);
         }
     }
 
-    public AbstractClassEnhancePluginDefine find(String enhanceClassName) {
+    public List<AbstractClassEnhancePluginDefine> find(String enhanceClassName) {
         if (pluginDefineMap.containsKey(enhanceClassName)) {
             return pluginDefineMap.get(enhanceClassName);
         }
diff --git a/apm-sniffer/apm-agent/src/main/java/org/skywalking/apm/agent/SkyWalkingAgent.java b/apm-sniffer/apm-agent/src/main/java/org/skywalking/apm/agent/SkyWalkingAgent.java
index e8afb5d11..2fe77d5ba 100644
--- a/apm-sniffer/apm-agent/src/main/java/org/skywalking/apm/agent/SkyWalkingAgent.java
+++ b/apm-sniffer/apm-agent/src/main/java/org/skywalking/apm/agent/SkyWalkingAgent.java
@@ -1,5 +1,6 @@
 package org.skywalking.apm.agent;
 
+import java.util.List;
 import net.bytebuddy.agent.builder.AgentBuilder;
 import net.bytebuddy.description.NamedElement;
 import net.bytebuddy.description.type.TypeDescription;
@@ -53,14 +54,22 @@ public class SkyWalkingAgent {
 
         new AgentBuilder.Default().type(enhanceClassMatcher(pluginFinder).and(not(isInterface()))).transform(new AgentBuilder.Transformer() {
             public DynamicType.Builder<?> transform(DynamicType.Builder<?> builder, TypeDescription typeDescription,
-                                                    ClassLoader classLoader) {
-                AbstractClassEnhancePluginDefine pluginDefine = pluginFinder.find(typeDescription.getTypeName());
-                return pluginDefine.define(typeDescription.getTypeName(), builder);
+                ClassLoader classLoader) {
+                List<AbstractClassEnhancePluginDefine> pluginDefines = pluginFinder.find(typeDescription.getTypeName());
+                for (AbstractClassEnhancePluginDefine pluginDefine : pluginDefines) {
+                    DynamicType.Builder<?> newBuilder = pluginDefine.define(typeDescription.getTypeName(), builder);
+                    if (newBuilder != null) {
+                        return newBuilder;
+                    }
+                }
+
+                logger.warn("Matched class {}, but enhancement fail.", typeDescription.getTypeName());
+                return builder;
             }
         }).with(new AgentBuilder.Listener() {
             @Override
             public void onTransformation(TypeDescription typeDescription, ClassLoader classLoader, JavaModule module,
-                                         DynamicType dynamicType) {
+                DynamicType dynamicType) {
 
             }